Publikace

2026

Kurfiřtová, E., Chvíla, S., Strnádková, N., Janoušková, V., Chytil, P., Etrych, T., Zbytovská, J. (2026). HPMA polymers as functional excipients in dermal nanoformulations of imiquimod. Int. J. Pharm. X, 11, 100486. DOI: 10.1016/j.ijpx.2026.100486

2025

Petrová, E.; Chvíla, S.; Štepánek, F.; Zbytovská, J.; Lamprou, D. A. (2025). Imiquimod nanocrystal loaded dissolving microneedles prepared by DLP printing. Drug Deliv Transl Res., 15, 158 170. DOI: 10.1007/s13346-024-01567-0

2024

Schild, J.; Kalvodová, A.; Zbytovská, J.; Farwick, M.; Pyko, C. (2024). The role of ceramides in skin barrier function and the importance of their correct formulation for skincare applications. Int. J. Cosmet. Sci., 46(4), 526 543. DOI: 10.1111/ics.12972

Odehnalová, K., Balouch, M., Storchmannová, K., Petrová, E., Konefał, M., Zadražil, A.; Berka, K.; Brus, J.; Štěpánek, F. (2024). Liposomal Copermeation Assay Reveals Unexpected Membrane Interactions of Commonly Prescribed Drugs. Mol. Pharm., 21(6), 2673 2683. DOI: 10.1021/acs.molpharmaceut.3c00766

2023

Petrová, E.; Chvíla, S.; Balouch, M.; Štěpánek, F.; Zbytovská, J. (2023). Nanoformulations for dermal delivery of imiquimod: The race of “soft” against “hard”. Int. J. Pharm., 648, 123577. DOI: 10.1016/j.ijpharm.2023.123577

Kalvodová, A., Dvořáková, K., Petrová, E., Michniak-Kohn, B.B., Zbytovská, J. (2023). The Contest of Nanoparticles: Searching for the Most Effective Topical Delivery of Corticosteroids. Pharmaceutics 15(2), 513. DOI: 10.3390/pharmaceutics15020513

2022

Kalvodová (Vovesná), A., Zbytovská, J. (2022). Lipid nanocapsules enhance the transdermal delivery of drugs regardless of their physico-chemical properties. Int. J. Pharm. 122264. DOI: 10.1016/j.ijpharm.2022.122264

Dvořáková, K., Štěpánek, P., Kroupová, J., & Zbytovská, J. (2021). N-Alkylmorpholines: Potent Dermal and Transdermal Skin Permeation Enhancers. Pharmaceutics, 14(1). DOI: 10.3390/pharmaceutics14010064

Čuříková-Kindlová, B. A., Vovesná, A., Nováčková, A., & Zbytovská, J. (2021). In Vitro Modeling of Skin Barrier Disruption and its Recovery by Ceramide-Based Formulations. AAPS PharmSciTech, 23(1), 21. DOI: 10.1208/s12249-021-02154-z

2021

Vovesná, A., Zhigunov, A., Balouch, M., & Zbytovská, J. (2021). Ceramide liposomes for skin barrier recovery: A novel formulation based on natural skin lipids. Int J Pharm, 596, 120264. DOI: 10.1016/j.ijpharm.2021.120264

Boltnarova, B., Kubackova, J., Skoda, J., Stefela, A., Smekalova, M., Svacinova, P., . . . Holas, O. (2021). Plga based nanospheres as a potent macrophage‐specific drug delivery system. Nanomaterials, 11(3), 1-17. DOI: 10.3390/nano11030749

Nováčková, A., Sagrafena, I., Pullmannová, P., Paraskevopoulos, G., Dwivedi, A., Mazumder, A., . . . Vávrová, K. (2021). Acidic pH Is Required for the Multilamellar Assembly of Skin Barrier Lipids In Vitro. Journal of Investigative Dermatology, 141(8), 1915-1921.e1914. DOI: 10.1016/j.jid.2021.02.014

Kubackova, J., Holas, O., Zbytovska, J., Vranikova, B., Zeng, G., Pavek, P., & Mullertz, A. (2021). Oligonucleotide delivery across the caco-2 monolayer: The design and evaluation of self-emulsifying drug delivery systems (sedds). Pharmaceutics, 13(4). DOI: 10.3390/pharmaceutics13040459

2020

Kubackova, J., Zbytovska, J., & Holas, O. (2020). Nanomaterials for direct and indirect immunomodulation: A review of applications. Eur J Pharm Sci, 142. DOI: 10.1016/j.ejps.2019.105139

2019

Čuříková-Kindlová, B. A., Diat, O., Štěpánek, F., Vávrová, K., & Zbytovská, J. (2019). Probing the interactions among sphingosine and phytosphingosine ceramides with non- and alpha-hydroxylated acyl chains in skin lipid model membranes. Int J Pharm, 563, 384-394. DOI: 10.1016/j.ijpharm.2019.04.010

Pullmannová, P., Ermakova, E., Kováčik, A., Opálka, L., Maixner, J., Zbytovská, J., . . . Vávrová, K. (2019). Long and very long lamellar phases in model stratum corneum lipid membranes. J Lipid Res, 60(5), 963-971. DOI: 10.1194/jlr.M090977

2017

Čuříková, B. A., Procházková, K., Filková, B., Diblíková, P., Svoboda, J., Kováčik, A., . . . Zbytovská, J. (2017). Simplified stratum corneum model membranes for studying the effects of permeation enhancers. Int J Pharm, 534(1), 287-296. DOI: 10.1016/j.ijpharm.2017.10.038

Pullmannová, P., Pavlíková, L., Kováčik, A., Sochorová, M., Školová, B., Slepička, P., . . . Vávrová, K. (2017). Permeability and microstructure of model stratum corneum lipid membranes containing ceramides with long (C16) and very long (C24) acyl chains. Biophysical Chemistry, 224, 20-31. DOI: 10.1016/j.bpc.2017.03.004

Sochorová, M., Staňková, K., Pullmannová, P., Kováčik, A., Zbytovská, J., & Vávrová, K. (2017). Permeability Barrier and Microstructure of Skin Lipid Membrane Models of Impaired Glucosylceramide Processing. Scientific Reports, 7(1). DOI: 10.1038/s41598-017-06990-7

Zbytovská, J., Gallusová, J., Vidlářová, L., Procházková, K., Šimek, J., & Štěpánek, F. (2017). Physical Compatibility of Propofol-Sufentanil Mixtures. Anesthesia and Analgesia, 124(3), 776-781. DOI: 10.1213/ANE.0000000000001720

2016

Vidlářová, L., Hanuš, J., Veselý, M., Ulbrich, P., Štěpánek, F., & Zbytovská, J. (2016a). Effect of lipid nanoparticle formulations on skin delivery of a lipophilic substance. Eur J Pharm Biopharm, 108, 289-296. DOI: 10.1016/j.ejpb.2016.07.016